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(1R,2S)-2-amino-1-methyl-2H-naphthalene-1-carboxylic acid

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Origin: China

Cas No: 157131-00-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 157131-00-5 Formula: C12H13NO2 Molecular Weight: 203.23700

Basic Info

Chemical Name	(1R,2S)-2-amino-1-methyl-2H-naphthalene-1-carboxylic acid
Synonyms
CAS No.	157131-00-5
Molecular Formula	C12H13NO2
Molecular Weight	203.23700
PSA	52.32000
LogP	1.99760

Synthesis Route

(1R,2S)-1-((S)-4-(tert-butyl)-4,5-dihydrooxazol-2-yl)-1-methyl-1,2-dihydronaphthalen-2-amine→(1R,2S)-2-amino-1-methyl-2H-naphthalene-1-carboxylic acid
1-[4'-(S)-tert-butyloxazolin-2'-yl]naphthalene→(1R,2S)-2-amino-1-methyl-2H-naphthalene-1-carboxylic acid
1-((1R,2S)-1-((S)-4-(tert-butyl)-4,5-dihydrooxazol-2-yl)-1-methyl-1,2-dihydronaphthalen-2-yl)piperidin-4-one→(1R,2S)-2-amino-1-methyl-2H-naphthalene-1-carboxylic acid

Precursor

1-Naphthoic Acid
8-((1R,2S)-1-((S)-4-(tert-butyl)-4,5-dihydrooxazol-2-yl)-1-methyl-1,2-dihydronaphthalen-2-yl)-1,4-dioxa-8-azaspiro[4.5]decane
1-[4'-(S)-tert-butyloxazolin-2'-yl]naphthalene
(1R,2S)-1-((S)-4-(tert-butyl)-4,5-dihydrooxazol-2-yl)-1-methyl-1,2-dihydronaphthalen-2-amine

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