Home > Chiral Compounds> (2,3,4,5,6-pentafluorophenyl) (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenylpropanoate

(2,3,4,5,6-pentafluorophenyl) (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenylpropanoate

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Origin: China

Cas No: 86060-92-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 86060-92-6 Formula: C30H20F5NO4 Molecular Weight: 553.47600

Basic Info

Chemical Name	(2,3,4,5,6-pentafluorophenyl) (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenylpropanoate
Synonyms	Fmoc-phenylalanine pentafluorophenyl ester; Fmoc-Phe-OPfp; N-(9-Fluorenylmethoxycarbonyl)-L-phenylalanine pentafluorophenyl ester; Fmoc-Phe pentafluorophenyl ester; Fmoc-L-Phe-OPfp; Fmoc-L-phenylalanine pentafluorophenyl ester; Fmoc-D-Phe-OPfp; Fmoc-Phe-OC6F5;
CAS No.	86060-92-6
Molecular Formula	C30H20F5NO4
Molecular Weight	553.47600
PSA	64.63000
LogP	6.82840

Properties

Appearance & Physical State	white crystals
Density	1.399g/cm3
Boiling Point	674.8ºC at 760 mmHg
Melting Point	149-151ºC(lit.)
Flash Point	361.9ºC
Refractive Index	1.588
Storage Condition	2-8ºC

Safety Info

Safety Statements	S22-S24/25
WGK Germany	3

Synthesis Route

Pentafluorophenol+9H-fluoren-9-ylmethyl N-[(2S)-1-chloro-1-oxo-3-phenylpropan-2-yl]carbamate→(2,3,4,5,6-pentafluorophenyl) (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenylpropanoate
FMOC-L-Phenylalanine+(2,3,4,5,6-pentafluorophenyl) 4-nitrobenzenesulfonate→(2,3,4,5,6-pentafluorophenyl) (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenylpropanoate
Pentafluorophenol+FMOC-L-Phenylalanine→(2,3,4,5,6-pentafluorophenyl) (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenylpropanoate

Precursor

(2,3,4,5,6-pentafluorophenyl) 4-nitrobenzenesulfonate
Pentafluorophenol
9H-fluoren-9-ylmethyl N-[(2S)-1-chloro-1-oxo-3-phenylpropan-2-yl]carbamate
PENTAFLUOROPHENYL TRIFLUOROACETATE

Downstream Product

L-lysyl-L-α-aspartyl-L-seryl-L-phenylalanyl-L-valyl-(αS,3R)-3-amino-α-(2-methylpropyl)-2-oxo-1-pyrrolidineacetyl-L-methioninamide
2-[[(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenylpropanoyl]amino]acetic acid
L-phenylalanine amide
N-CBZ-D-PHE-PHE-GLY

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