Home > Organosilicon Compounds> (3R,4R,5S)-4-(4-hydroxyphenyl)-5-tri(propan-2-yl)silyloxypiperidin-3-ol

(3R,4R,5S)-4-(4-hydroxyphenyl)-5-tri(propan-2-yl)silyloxypiperidin-3-ol

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Origin: China

Cas No: 873945-31-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 873945-31-4 Formula: C20H35NO3Si Molecular Weight: 365.58200

Basic Info

Chemical Name	(3R,4R,5S)-4-(4-hydroxyphenyl)-5-tri(propan-2-yl)silyloxypiperidin-3-ol
Synonyms	4-(4-hydroxyphenyl)-5-triisopropylsilanyloxypiperidin-3-ol; (3R,4R,5S)-4-(4-hydroxyphenyl)-5-((triisopropylsilyl)oxy)piperidin-3-ol; (3R,4R,5S)-4-(4-Hydroxyphenyl)-5-[[tris(1-methylethyl)silyl]oxy]-3-piperidinol; (3R,4R,5S)-4-(4-hydroxy-phenyl)-5-triisopropylsilanyloxy-piperidin-3-ol;
CAS No.	873945-31-4
Molecular Formula	C20H35NO3Si
Molecular Weight	365.58200
PSA	61.72000
LogP	4.32940

Synthesis Route

(3R,4R,5S)-4-(4-benzyloxy-phenyl)-1-((R)-1-phenyl-ethyl)-5-triisopropylsilanyloxy-piperidin-3-ol→(3R,4R,5S)-4-(4-hydroxyphenyl)-5-tri(propan-2-yl)silyloxypiperidin-3-ol
(3S)-4-(4-benzyloxy-phenyl)-1-[(1R)-phenyl-ethyl]-1,2,3,6-tetrahydro-pyridin-3-ol→(3R,4R,5S)-4-(4-hydroxyphenyl)-5-tri(propan-2-yl)silyloxypiperidin-3-ol

Precursor

(3S)-4-(4-benzyloxy-phenyl)-1-[(1R)-phenyl-ethyl]-1,2,3,6-tetrahydro-pyridin-3-ol
(3R,4R,5S)-4-(4-benzyloxy-phenyl)-1-((R)-1-phenyl-ethyl)-5-triisopropylsilanyloxy-piperidin-3-ol

Downstream Product

benzyl (3R,4R,5S)-3-hydroxy-4-(4-hydroxyphenyl)-5-tri(propan-2-yl)silyloxypiperidine-1-carboxylate

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