Home > Organosilicon Compounds> (3R,4S)-4-phenyl-3-triethylsilyloxyazetidin-2-one

(3R,4S)-4-phenyl-3-triethylsilyloxyazetidin-2-one

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Origin: China

Cas No: 149140-54-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Property

CAS No.: 149140-54-5 Formula: C15H23NO2Si Molecular Weight: 277.43400

Basic Info

Chemical Name	(3R,4S)-4-phenyl-3-triethylsilyloxyazetidin-2-one
Synonyms	4-phenyl-3-triethylsilanyloxy-azetidin-2-one;
CAS No.	149140-54-5
Molecular Formula	C15H23NO2Si
Molecular Weight	277.43400
PSA	41.82000
LogP	3.52380

Properties

Density	1.04g/cm3
Boiling Point	393.216ºC at 760 mmHg
Flash Point	191.611ºC
Refractive Index	1.516
Vapor Pressure	0mmHg at 25°C

Synthesis Route

Chlorotriethylsilane+(3R,4S)-3-Hydroxy-4-phenylazetidin-2-one→(3R,4S)-4-phenyl-3-triethylsilyloxyazetidin-2-one
methyl (2R,3S)-3-amino-3-phenyl-2-(triethylsilyloxy)propanoate→(3R,4S)-4-phenyl-3-triethylsilyloxyazetidin-2-one
1H-imidazole+azetidin-2-one→(3R,4S)-4-phenyl-3-triethylsilyloxyazetidin-2-one

Precursor

azetidin-2-one
(3R,4S)-3-Hydroxy-4-phenylazetidin-2-one
Chlorotriethylsilane
methyl (2R,3S)-3-amino-3-phenyl-2-(triethylsilyloxy)propanoate

Downstream Product

(3R,4S)-1-t-Boc-3-[(triethylsilyl)oxy]-4-phenyl-2-azatidinone
(3R,4S)-1-benzoyl-4-phenyl-3-triethylsilyloxyazetidin-2-one

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