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Picture of (6α,8ξ,10ξ,11β,14ξ,16α,17α)-6,9-Difluoro-11-hydroxy-16-methyl-17- [(methylsulfanyl)carbonyl]-3-oxoandrosta-1,4-dien-17-yl propionat e

(6α,8ξ,10ξ,11β,14ξ,16α,17α)-6,9-Difluoro-11-hydroxy-16-methyl-17- [(methylsulfanyl)carbonyl]-3-oxoandrosta-1,4-dien-17-yl propionat e

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Origin: China

Cas No: 73205-13-7

Specification: 99%min

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  • Products Specification
  • Product Description
  • Property

    CAS No.: 73205-13-7 Formula: C25H32F2O5S Molecular Weight: 482.58000

    Description

    Ticabesone Propionate is an impurity of Fluticasone, an antiallergic, anti-asthmatic and anti-inflammatory agent.

    Basic Info

    Chemical Name (6α,8ξ,10ξ,11β,14ξ,16α,17α)-6,9-Difluoro-11-hydroxy-16-methyl-17- [(methylsulfanyl)carbonyl]-3-oxoandrosta-1,4-dien-17-yl propionat e
    Synonyms

    Carbamothioic acid,(4-methylphenyl)-,S-methyl ester;
    p-tolyl-thiocarbamic acid S-methyl ester;
    S-methyl 4-tolylcarbamothioate;
    S-methyl N-(4-methylphenyl)thiocarbamate;
    S-methyl p-tolylcarbamothioate;
    p-Tolyl-thiocarbamidsaeure-S-methylester;

    CAS No. 73205-13-7
    Molecular Formula C25H32F2O5S
    Molecular Weight 482.58000
    PSA 105.97000
    LogP 4.13280

    Properties

    Density 1.29g/cm3
    Boiling Point 569.4ºC at 760 mmHg
    Flash Point 298.2ºC
    Refractive Index 1.563

    Synthesis Route

    (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-17-carboxylic acid(6α,8ξ,10ξ,11β,14ξ,16α,17α)-6,9-Difluoro-11-hydroxy-16-methyl-17- [(methylsulfanyl)carbonyl]-3-oxoandrosta-1,4-dien-17-yl propionat e
    diflorasone(6α,8ξ,10ξ,11β,14ξ,16α,17α)-6,9-Difluoro-11-hydroxy-16-methyl-17- [(methylsulfanyl)carbonyl]-3-oxoandrosta-1,4-dien-17-yl propionat e
    (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-propanoyloxy-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-17-carboxylic acid(6α,8ξ,10ξ,11β,14ξ,16α,17α)-6,9-Difluoro-11-hydroxy-16-methyl-17- [(methylsulfanyl)carbonyl]-3-oxoandrosta-1,4-dien-17-yl propionat e

    Precursor

    (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-17-carboxylic acid
    Sodium thiomethoxide
    diflorasone
    (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-propanoyloxy-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-17-carboxylic acid

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