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Picture of 7-methoxy-4-methyl-3,5-dihydro-2H-1,4-benzothiazepine

7-methoxy-4-methyl-3,5-dihydro-2H-1,4-benzothiazepine

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Origin: China

Cas No: 927871-76-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

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  • Products Specification
  • Product Description
  • Property

    CAS No.: 927871-76-9 Formula: C11H15NOS Molecular Weight: 209.30800

    Description

    It is a benzothiazepine derivative that binds the RyR1 channel and enhances the binding affinity of Calstabin-1. By preventing the depletion of Calstabin-1 from the RyR1 complex, S 107 slows muscle fatique and reduces muscle damage in exercised mice. In a murine model of Duchenne muscular dystrophy, S 107 reduces biochemical and histological evidence of the muscle damage associated with muscular dystrophy, improves muscle function, and increases exercise performance.

    Basic Info

    Chemical Name 7-methoxy-4-methyl-3,5-dihydro-2H-1,4-benzothiazepine
    Synonyms

    S107;
    2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine;
    2,3,3',4,4',6-HEXACHLOROBIPHENYL;

    CAS No. 927871-76-9
    Molecular Formula C11H15NOS
    Molecular Weight 209.30800
    PSA 37.77000
    LogP 2.17060

    Synthesis Route

    7-methoxy-2,3,4,5-tetrahydro-1,4-benzothiazepine+Formaldehyde7-methoxy-4-methyl-3,5-dihydro-2H-1,4-benzothiazepine
    6-methoxy-3,4-dihydro-2H-[1]benzothiopyran-4-one7-methoxy-4-methyl-3,5-dihydro-2H-1,4-benzothiazepine
    4-METHOXYBENZENETHIOL7-methoxy-4-methyl-3,5-dihydro-2H-1,4-benzothiazepine

    Precursor

    Formaldehyde
    7-methoxy-2,3,4,5-tetrahydro-1,4-benzothiazepine
    6-methoxy-3,4-dihydro-2H-[1]benzothiopyran-4-one
    4-METHOXYBENZENETHIOL

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