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9-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine

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Origin: China

Cas No: 3454-96-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

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CAS No.: 3454-96-4 Formula: C18H18ClN3O Molecular Weight: 327.80800

Description

3-Chloro Loxapine is an related compound to Loxapine, a D2/D4-Dopamine receptor antagonist. A serotonergic receptor antagonist. A dibenzoxazepine antipsychotic agent.

Basic Info

Chemical Name	9-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine
Synonyms	UNII-B493L6YTDM; Loxapine related compound A;
CAS No.	3454-96-4
Molecular Formula	C18H18ClN3O
Molecular Weight	327.80800
PSA	28.07000
LogP	3.08280

Synthesis Route

3-chloro-10H-dibenzo[b,f][1,4]oxazepin-11-one→9-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine
1-Methylpiperazine+3,11-dichloro-dibenzo[b,f][1,4]oxazepine→9-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine

Precursor

1-Methylpiperazine
3-chloro-10H-dibenzo[b,f][1,4]oxazepin-11-one
3,11-dichloro-dibenzo[b,f][1,4]oxazepine

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